Category Archives: Hypogonadism Management

Reading Time: 4 minutesTestosterone deficiency is frequently seen in both men and women with HIV. Endocrine abnormalities, which can affect testosterone production, have long been recognized as a complication of HIV since the earliest days of the pandemic (although it has generally been associated with late stage disease). However, recent research has shown that nearly one out of every five men with HIV has documented testosterone deficiency, irrespective of CD4 count, viral load, or treatment status. Similarly, testosterone deficiency is seen in one in four HIV-positive women, most often in the context of severe, unexplained weight loss (HIV wasting). Testosterone is the steroid … Read more »

Reading Time: < 1 minuteHypogonadism can begin during fetal development, before puberty or during adulthood. Signs and symptoms depend on when the condition develops. If the body doesn't produce enough testosterone during fetal development, the result may be impaired growth of the external sex organs. Depending on when hypogonadism develops and how much testosterone is present, a child who is genetically male may be born with: Male hypogonadism may delay puberty or cause incomplete or lack of normal development. It can cause: In adult males, hypogonadism may alter certain masculine physical characteristics and impair normal reproductive function. Signs and symptoms may include: Hypogonadism can … Read more »

Reading Time: 2 minutesRepros Therapeutics Inc. ( RPRX ) announced it has completed enrollment for one of the two head-to-head studies on its secondary hypogonadism candidate, Androxal. The two identical, 17-week, double-blind studies will compare the safety and efficacy of Androxal with a testosterone replacement therapy (topical gel) and placebo in restoring and maintaining testicular function. The primary endpoint of the study is to find if Androxal is superior to both placebo and the topical gel based on normal testosterone levels and normal sperm concentrations achieved by patients. While the first study (ZA-305) enrolled 120 men, the second study (ZA-304) will also enroll … Read more »

Reading Time: < 1 minuteOn each valid NATESTO prescription or refill, we would like to offer a 5% discount. The patient is responsible for any balance remaining, and for reporting receipt of this coupon benefit. Offer only valid for male or female patients over age 30 who will pay out of pocket. Offer good only in USA and void where prohibited by law, taxed, or restricted. … Read more »

Reading Time: < 1 minuteMale hypogonadism pathophysiology By: dave cohen Go here to see the original: Male hypogonadism pathophysiology - Video … Read more »

Reading Time: < 1 minuteRepros Therapeutics Inc. said it was notified by the U.S. Food and Drug Administration that there isnt enough clinical information to hold a planned pre-investigational new drug application meeting in November. Its shares RPRX, -39.96% dropped 43% in premarket trade in response. The stock had already lost more than half its value through Thursdays close in the past 12 months. The company in September said it had been granted a type B, pre-investigational new-drug application meeting with the FDA in the first half of November, when Repros planned to seek guidance on its planned new drug application for Androxal for … Read more »

Reading Time: 2 minutesNEW YORK, Sept. 29, 2014 /PRNewswire-USNewswire/ --Androxal(R) Second Pivotal Study from Repros Therapeutics Inc. (NASDAQ: RPRX) a development stage biopharmaceutical company, achieves superiority in top line analysis for both co-primary endpoints compared to marketed topical gel in the treatment of secondary hypogonadism. However, the conclusions of the FDA Advisory Panel that met on Wednesday, September 17, 2014, to discuss the appropriate population suited to testosterone replacement therapy (TRT), were not directly related to Androxal(R), since Androxal(R) is not a form of testosterone. The FDA panelists voted to recommend that testosterone replacement class label should be changed, narrowing the treatment option … Read more »

Reading Time: < 1 minuteHypogonadism can occur for a number of reasons. Certain men have hypogonadism since birth while others may develop this condition later in life. Two types of hypogonadism are: Primary hypogonadism (testicular failure) - Low serum testosterone levels and gonadotropins (FSH, LH) above the normal range. Hypogonadotropic hypogonadism - Idiopathic gonadotropin or LHRH deficiency or pituitary - hypothalamic injury from tumors, trauma, or radiation. Characterized by low serum testosterone levels, but with gonadotropins in the normal or low range. Men develop testicular suppression with decreased libido, impotence, decreased ejaculate volume, loss of body and facial hair, weakness, fatigue and often anemia. … Read more »

Reading Time: < 1 minuteMale Hypogonadism 1/28/15 MGMC Physician Grand Rounds, 1/28/15 Rami Almokayyad, MD, Endocrinology McFarland Clinic. By: Mary Greeley Medical Center Excerpt from: Male Hypogonadism 1/28/15 - Video … Read more »

Reading Time: < 1 minuteBy RTT News, March 06, 2014, 07:29:00 AM EDT (RTTNews.com) - Endo International plc. (ENDP, ENL.TO) announced that its operating company Endo Pharmaceuticals Inc. received U.S. Food and Drug Administration or FDA approval of AVEED (testosterone undecanoate) injection for the treatment of adult men with hypogonadism (commonly known as Low-T) that is associated with a deficiency or absence of the male hormone testosterone. The company stated that AVEED is a new prescription medicine indicated to produce serum testosterone levels in the normal range by administration of a single 3-mL (750 mg) intramuscular injection given once at initiation of therapy, at … Read more »

Reading Time: < 1 minuteVLog #127 Frances Explains Hypogonadism. Good evening You Tubers. Wickedpedia has some good information about Physical conditions that male and female People have regarding their glands that produce the hormones that control one's... By: Frances MaGinness Continue reading here: VLog #127 Frances Explains Hypogonadism. - Video … Read more »

Reading Time: < 1 minuteHypogonadism is a condition that results in lowered function of the testis in males or ovaries in females. This condition can be present at birth, but may also develop after infection or injury. There are two types of hypogonadism. Primary hypogonadism is caused by a problem with the testis or the ovaries. Secondary hypogonadism (hypogonadotropic hypogonadism) is caused by pituitary or hypothalamic gland disorders. Complications of hypogonadism in newborns may include abnormal genitals. In pubescent boys, lack of treatment can result in impaired genital growth, absence of body hair, and enlarged breasts. Complications in untreated adult males include: Complications in … Read more »

Reading Time: < 1 minuteHypogonadism (Medical Condition) Symptoms, risk factors and treatments of Hypogonadism (Medical Condition) Hypogonadism is a medical term which describes a diminished functional activity of the gonads the testes... By: Medical Condition Information Follow this link: Hypogonadism (Medical Condition) - Video … Read more »

Reading Time: < 1 minuteLow Testosterone (Hypogonadism) in Men Email us at kababayan@la18.tv for story suggestions. Like us on Facebook at https://www.facebook.com/kababayanla18. Follow us on Twitter at https://twitter.c... By: Kababayan Today Read more: Low Testosterone (Hypogonadism) in Men - Video … Read more »

Reading Time: < 1 minuteTestosterone levels in men decline with age, at a rate of about 1% per year beginning at about 40 years old.3 Epidemiological studies have determined that total testosterone follows an age-related decline with mean serum concentration at the age of 75 years approximately two thirds that at 25 years.4 According to reports, approximately 74% of chronic opioid users5, 50% of AIDS patients6, 52% of obese men7, 50% of diabetic men7,8 have low testosterone. Other causes of lowered testosterone levels include: injury, infection, or loss of the testicles; chemotherapyor radiation treatment for cancer; genetic abnormalities such as Klinefelter's Syndrome (extra X … Read more »

Reading Time: < 1 minuteMale Hypogonadism What is Male Hypogonadism? Male hypogonadism is the inability of the testicles to produce testosterone, sperm or both. Male hypogonadism also is called testosterone deficiency. What are Testicles? Testicles are external genital organs that are part of the male reproductive system. These two oval-shaped organs reside in a pouch of skin that hangs below the abdomen and behind the penis. The skin of pouch that contains the testicles is called the scrotum. In addition to producing the sperm cells that are necessary for reproduction, the testicles secrete the male hormone testosterone. Testosterone plays an important role in the … Read more »

Reading Time: < 1 minuteWhat is Hypogonadism? Hypogonadism occurs when your sex glands produce little or no sex hormones. The sex glands, also called gonads, are the testes in men and the ovaries in women. Sex hormones help control sex characteristics, such as breast and testicle development, and pubic hair growth. Sex hormones also play a role in menstrual cycles and sperm production. Hypogonadism may also be called gonad deficiency. In males, it may be called low serum testosterone or andropause. Most cases of this disorder can be successfully treated. 9 Warning Signs of Low Testosterone There are two types of hypogonadism: primary and … Read more »

Reading Time: 2 minutesEndo International ( ENDP ) was up 3.3% after the company announced that it has entered into an agreement to acquire the rights to Natesto (testosterone nasal gel) from Trimel BioPharma SRL, a wholly owned subsidiary of Trimel Pharmaceuticals Corp. ( TRLPF ). Endo expects to complete the transaction in early 2015. The FDA has cleared Natesto in May 2014 for replacement therapy in males for conditions associated with a deficiency or absence of endogenous testosterone including primary hypogonadism (congenital or acquired) and hypogonadotropic hypogonadism (congenital or acquired). As per the terms of the agreement, Endo will acquire sole and … Read more »

Reading Time: < 1 minuteHypogonadism r en endokrin sjukdom dr knskrtlarna har en bristfllig funktion, vilket resulterar i fr lg eller ingen produktion av knshormoner, det vill sga till exempel testosteron eller strogen. Tillstndet leder obehandlat bland annat till bristfllig utveckling av spermier eller ggfollikler hos vuxna och bristfllig pubertet hos barn och unga. Hypogonadism hos mn ska inte frvxlas med testosteronbrist, som kan ha andra orsaker. I synnerhet hos ldre mn kan hypogonadism antingen bero p dligt fungerande knskrtlar, eller p problem med fristtningshormonkrtlarna hypotalamus och hypofysen. Testosteronniverna kan vara lga tillflligt eller bero p andra sjukdomar, ssom diabetes, hjrtsvikt eller annan hjrt- … Read more »

Reading Time: 2 minutesIn men 45 and older, most cases of hypogonadism or Low-T often go overlooked due to the fact that the symptoms may be more general in nature and slower in onset. Many men simply attribute their symptoms to aging and often dismiss them because they don't think that there is anything that they can do about them. This is largely because the symptoms of hypogonadism are nearly identical to those experienced by men going through andropause (the male menopause): low libido, fatigue, depression, memory loss, difficulty concentrating and irritability. The difference between andropause and hypogonadism is simple. Andropause is a … Read more »