Category Archives: HYPOGONADISM

Reading Time: < 1 minuteTORONTO, ONTARIO--(Marketwire - Oct 29, 2012) - Trimel Pharmaceuticals Corporation (TRL.TO) (the "Company" or "Trimel") will report on the third quarter financial results for the Company and its subsidiaries for the period ended September 30, 2012 on Wednesday, November 7, 2012after the market closes. Management of the Company will host a conference call to discuss these results and update investors on the status of its business on Thursday, November 8, 2012, at 8:30 a.m. Eastern Standard Time. Presenting from Trimel will be Bruce Brydon, Chairman of the Board and Chief Executive Officer, Tom Rossi, President and Chief Operating Officer and … Read more »

Reading Time: < 1 minuteLow testosterone (Low-T) definition Testosterone is a hormone required for male development and is produced primarily in the testicles. It is responsible for building muscle and bone mass as well as sperm production and sex drive. It influences male pattern fat distribution, bone density, and red blood cell production. Lack of or underproduction of testosterone either directly due to decreased production in the testes or indirectly due to lack of stimulation of the testes to produce testosterone by the pituitary gland is called hypogonadism and is a medical condition requiring treatment. In the normal developing male, testosterone peaks during early … Read more »

Reading Time: < 1 minuteDUBLIN--(BUSINESS WIRE)-- Research and Markets has announced the addition of the "Male Hypogonadism Global Clinical Trials Review, H1, 2013" report to their offering. Male Hypogonadism Global Clinical Trials Review, H1, 2013 provides data on the Male Hypogonadism clinical trial scenario. This report provides elemental information and data relating to the clinical trials on Male Hypogonadism. It includes an overview of the trial numbers and their recruitment status as per the site of trial conduction across the globe. The databook offers a preliminary coverage of disease clinical trials by their phase, trial status, prominence of the sponsors and also provides briefing … Read more »

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Reading Time: 2 minutesScienceDaily (Oct. 16, 2012) A study by the University at Buffalo shows for the first time that obese males ages 14 to 20 have up to 50 percent less total testosterone than do normal males of the same age, significantly increasing their potential to be impotent and infertile as adults. The paper was published online as an accepted article in Clinical Endocrinology. The authors are the same researchers in the University at Buffalo's School of Medicine and Biomedical Sciences who first reported in 2004 the presence of low testosterone levels, known as hypogonadism, in obese, type 2 diabetic adult males … Read more »

Reading Time: < 1 minute(See also Male Hypogonadism in Children.) Hypogonadism is defined as testosterone deficiency with associated symptoms or signs, deficiency of spermatozoa production, or both. It may result from a disorder of the testes (primary hypogonadism) or of the hypothalamic-pituitary axis (secondary hypogonadism). Both may be congenital or acquired as the result of aging, disease, drugs, or other factors. Additionally, a number of congenital enzyme deficiencies cause varying degrees of target organ androgen resistance. Diagnosis is confirmed by hormone levels. Treatment varies with etiology but typically includes gonadotropin-releasing hormone, gonadotropin, or testosterone replacement. Primary hypogonadism involves failure of the testes to respond … Read more »

Reading Time: < 1 minuteHypergonadotropic hypogonadism (HH), also known as primary or peripheral/gonadal hypogonadism, is a condition which is characterized by hypogonadism due to an impaired response of the gonads to the gonadotropins, follicle-stimulating hormone (FSH) and luteinizing hormone (LH), and in turn a lack of sex steroid production and elevated gonadotropin levels (as an attempt of compensation by the body). HH may present as either congenital or acquired, but the majority of cases are of the former nature.[1][2] There are a multitude of different etiologies of HH. Congenital causes include the following:[1][3][4] Acquired causes (due to damage to or dysfunction of the gonads) … Read more »

Reading Time: 3 minutesAll men undergoing fertility testing will be checked for hormonal imbalances that could be contributing to their infertility. One important hormone necessary for proper sexual functioning in men is testosterone. When a man is found to have a testosterone deficiency, it can signal a common disorder known as hypogonadism. What Does Testosterone Do? Testosterone, often referred to as the male hormone although females do produce small amounts of the hormone as well, is a hormone that is produced in the testicles. It is responsible for the growth and development of the sex and reproductive organs in men. Additionally, testosterone contributes … Read more »

Reading Time: 3 minutesServices and Web Sites Covered This policy describes what information may be collected about you when you use the services made available through the WebMD Health Professional Network (as defined below), how this information may be used, how you can control how your information is used and what precautions are taken against unauthorized access or use of your information. The services made available through the WebMD Health Professional Network may be provided in a variety of mediums and devices now known or hereinafter developed including mobile applications, and include without limitation news, reference tools and applications, sponsored programming, personalized content, … Read more »

Reading Time: < 1 minuteHypogonadismoccurs when the body's sex glands produce little or no hormones. In men, these glands (gonads) are the testes. In women, these glandsare the ovaries. The cause of hypogonadismis primary or central. In primary hypogonadism, the ovaries or testes themselves do not function properly. Causes of primary hypogonadism include: The most common genetic disorders that cause primary hypogonadism are Turner syndrome (in women) and Klinefelter syndrome (in men). In central hypogonadism, the centers in the brain that control the gonads (hypothalamus and pituitary) do not function properly. Causes of central hypogonadism include: A genetic cause of central hypogonadism that also … Read more »

Reading Time: < 1 minuteDefinition Hypogonadism is when the sex glands produce little or no hormones. In men, these glands (gonads) are the testes; in women, they are the ovaries. Gonadal deficiency The cause of hypogonadism may be "primary" or "central." In primary hypogonadism, the ovaries or testes themselves do not function properly. Some causes of primary hypogonadism include: The most common genetic disorders that cause primary hypogonadism are Turner syndrome (in women) and Klinefelter syndrome (in men). In central hypogonadism, the centers in the brain that control the gonads (hypothalamus and pituitary) do not function properly. Some causes of central hypogonadism include: A … Read more »

Reading Time: < 1 minuteCauses, signs and symptoms of hypogonadism Hypogonadism is a reduction or absence of hormone secretions from the sex glands (gonads). In men the hormones are secreted from the testes; in women the hormones come from the ovaries. Many types of hypogonadism can be treated and the condition does have a good prognosis. There are two types of hypogonadism; Primary, where the testes fail to function properly, and Central hypogonadism where the centers of the brain responsible for control of the gonads (the hypothalamus and pituitary) do not function properly. Causes of primary and central hypogonadism Primary hypogonadism occurs for a … Read more »

Reading Time: 2 minutesWashington, October 17 (ANI): Obese males ages 14 to 20 have up to 50 percent less total testosterone than do normal males of the same age, significantly increasing their potential to be impotent and infertile as adults. This is according to a study by the University at Buffalo. The researchers are the same ones in the University at Buffalo's School of Medicine and Biomedical Sciences who first reported in 2004 the presence of low testosterone levels, known as hypogonadism, in obese, type 2 diabetic adult males and confirmed it in 2010 in more than 2,000 obese men, both diabetic and … Read more »

Reading Time: < 1 minuteDUBLIN--(BUSINESS WIRE)-- Research and Markets (http://www.researchandmarkets.com/research/3sqllb/male_hypogonadism) has announced the addition of Global Markets Direct's new report "Male Hypogonadism - Pipeline Review, H2 2012" to their offering. Global Markets Direct's, 'Male Hypogonadism - Pipeline Review, H2 2012', provides an overview of the Male Hypogonadism therapeutic pipeline. This report provides information on the therapeutic development for Male Hypogonadism, complete with latest updates, and special features on late-stage and discontinued projects. It also reviews key players involved in the therapeutic development for Male Hypogonadism. 'Male Hypogonadism - Pipeline Review, H2 2012' is built using data and information sourced from Global Markets Direct's proprietary … Read more »

Reading Time: < 1 minuteWhat is Hypogonadism? Hypogonadism occurs when your sex glands produce little or no sex hormones. The sex glands, also called gonads, are the testes in men and the ovaries in women. Sex hormones help control sex characteristics, such as breast and testicle development, and pubic hair growth. Sex hormones also play a role in menstrual cycles and sperm production. Hypogonadism may also be called gonad deficiency. In males, it may be called low serum testosterone or andropause. Most cases of this disorder can be successfully treated. 9 Warning Signs of Low Testosterone There are two types of hypogonadism: primary and … Read more »

Reading Time: 2 minutesTORONTO, ONTARIO--(Marketwire - Oct 15, 2012) - Trimel Pharmaceuticals Corporation (TRL.TO) ("the "Company" or "Trimel") today announced progress on three of its product candidates: CompleoTRT Phase III Efficacy Completed The Company announced today that all patients have completed dosing of CompleoTRT for the efficacy portion of the Phase III clinical trial evaluating its lead product in patients with male hypogonadism or more commonly referred to as "Low T".The unique delivery of Compleo TRT is designed to provide hypogonadal men with the therapeutic effect of restoring testosterone levels while doing so with a micro volume amount of drug in the form … Read more »

Reading Time: < 1 minuteSigns Symptoms of Hypogonadism Dr. Richard Bebb is a Clinical Assistant Professor of Endocrinology and Metabolism at the University of British Columbia.From:aboutmenshealthViews:717 0ratingsTime:00:40More inPeople Blogs See more here: Signs … Read more »

Reading Time: < 1 minuteLINCOLNSHIRE, Ill.--(BUSINESS WIRE)-- BioSante Pharmaceuticals, Inc. (BPAX) today announced that Stephen M. Simes, BioSantes president & CEO, will present a corporate update at the 11th Annual BIO Investor Forum hosted by the Biotechnology Industry Organization (BIO). The BIO Investor Forum, which features leading private and emerging public companies, will take place October 9-10, 2012 at the Palace Hotel in San Francisco, CA. The BIO Investor Forum is an international investor conference featuring leading private and emerging public biotech companies. Information about the conference is available at http://www.bio.org/events/conferences/11th-annual-bio-investor-forum. About BioSante Pharmaceuticals, Inc. BioSantes corporate strategy is to develop high value medically-needed … Read more »

Reading Time: 2 minutesLow serum testosterone, also known as hypogonadism or Andropause, affects roughly 39% of men over the age of 45. The prevalence of low testosterone increases with age. Researcher have found that the incidence of low testosterone increases from approximately 20% of men over 60, to 30% of men over 70 and 50% of men over 80 years of age. What are the signs of low testosterone in men? There are both sexual and non-sexual signs and symptoms associated with low testosterone. Sexual symptoms include poor erectile function, low libido (desire for sex), weaker and fewer erections, and reduced sexual activity. … Read more »

Reading Time: 3 minutesCHESTERBROOK, Pa., Jan. 27, 2015 /PRNewswire/ --Auxilium Pharmaceuticals, Inc. (NASDAQ: AUXL), a specialty biopharmaceutical company, announced that it held a special meeting of its stockholders today at 8:30 a.m. ET to approve matters relating to the previously announced proposed merger with Endo International plc. The proposal to adopt the amended and restated agreement and plan of merger was passed by stockholders with approximately 84 percent of outstanding shares voting in favor. Auxilium anticipates that the proposed merger transaction will close on Thursday, January 29, 2015. "As we near the anticipated close of the transaction, I would like to take a … Read more »